BEGIN:VCALENDAR
VERSION:2.0
PRODID:https://murmitoyen.com/events/vanille/udem/
X-WR-TIMEZONE:America/Montreal
BEGIN:VEVENT
UID:69da59570b4d9
DTSTAMP:20260411T102319
DTSTART:20180926T110000
SEQUENCE:0
TRANSP:OPAQUE
DTEND:20180926T110000
URL:https://murmitoyen.com/events/vanille/udem/detail/832715-conference-de-
 chimie-avec-le-professeur-jerome-waser-de-lepfl-suisse
LOCATION:Université de Montréal - Pavillon Roger-Gaudry\, 2900\, chemin d
 e la Tour\, Montréal\, QC\, Canada\, H3T 1J6
SUMMARY:Conférence de chimie avec le professeur Jérôme Waser de l'EPFL\,
  Suisse
DESCRIPTION:Titre: ‘‘ Hypervalent Iodine Reagents for the Functionali
 zation of DiazoCompounds and Radicals ’’
\n 
\nEndroit : Pavillon R
 oger-Gaudry\, salle S-142 
\n 
\nHeure : 11:00 AM
\n 
\nHôte : Profes
 seure Hélène Lebel
\n 
\nRésumé :
\n The non-classical four-electr
 on three-center bonds of hypervalent iodine reagents are weaker than norma
 l classical bonds. This confers an exceptional reactivity to these compoun
 ds as oxidants or atom-transfer reagents. Cyclic hypervalent iodine reagen
 ts are especially interesting\, as they combine enhanced stability with un
 ique opportunities for reactivity modulation.1 In particular\, our group h
 as been interested in the development of alkynylation methods using cyclic
  EthynylBenziodoXolone (EBX) hypervalent iodine reagents. These reagents c
 an be used to transfer alkynes to the C-H bonds of heterocycles\,2 C-C dou
 ble bonds3 or hetero atom nucleophiles.4 They were also successful in the 
 oxyalkynylation of diazo compounds.5  The use of cyclic hypervalent iodin
 e reagents is not limited to alkynylation. Recently\, we also demonstrated
  their use for azidation6 and cyanation\,7 and their use for trifluorometh
 ylation (Togni reagents) is now well established.8  Herein\, our most rec
 ent results in the use of cyclic hypervalent iodine reagents for the funct
 ionalization of diazo compounds and radicals will be presented.
\n(1) Revi
 ew: Y. Li\, D. P. Hari\, M. V. Vita\, J. Waser\, Angew. Chem.\, Int. Ed. 2
 016\, 55\, 4436.
\n(2) J. P. Brand\, J. Charpentier\, J. Waser\, Angew. Ch
 em.\, Int. Ed. 2009\, 48\, 9346.
\n(3) S. Nicolai\, C. Piemontesi\, J. Was
 er\, Angew. Chem.\, Int. Ed. 2011\, 50\, 4680.
\n(4) R. Frei\, M. D. Wodri
 ch\, D. P. Hari\, P. A. Borin\, C. Chauvier\, J. Waser\, J. Am. Chem. Soc.
  2014\, 136\, 16563.
\n(5) D. P. Hari\, J. Waser\, J. Am. Chem. Soc. 2016\
 , 138\, 2190.
\n(6) S. Alazet\, F. Le Vaillant\, S. Nicolai\, T. Courant\,
  J. Waser\, Chem. Eur. J. 2017\, 23\, 9501.
\n(7) F. Le Vaillant\, M. D. W
 odrich\, J. Waser\, Chem. Sci. 2017\, 8\, 1790.
\n(8) J. Charpentier\, N. 
 Frueh\, A. Togni\, Chem. Rev 2015\, 115\, 650.
\nInformations supplémenta
 ires
\n 
\nAnnonce PDF de la conférence
END:VEVENT
BEGIN:VTIMEZONE
TZID:America/Montreal
X-LIC-LOCATION:America/Montreal
END:VTIMEZONE
END:VCALENDAR