BEGIN:VCALENDAR
VERSION:2.0
PRODID:https://murmitoyen.com/events/vanille/udem/
X-WR-TIMEZONE:America/Montreal
BEGIN:VEVENT
UID:69db5fa8bde19
DTSTAMP:20260412T050232
DTSTART:20170920T110000
SEQUENCE:0
TRANSP:OPAQUE
DTEND:20170920T110000
URL:https://murmitoyen.com/events/vanille/udem/detail/783206-tuning-molecul
 ar-recognition-in-dna-materials
LOCATION:Pavillon Roger-Gaudry \, 2900\, boul. Édouard-Montpetit\, Local M
 -415\, Montréal\, QC\, Canada
SUMMARY:Tuning Molecular Recognition in DNA Materials
DESCRIPTION:Titre :Tuning Molecular Recognition in DNA Materials: Towards S
 elf-Replicating Systems and Smarter Particules
\nEndroit : Pavillon Roger-
 Gaudry\, Salle N-615Hôte : Jean-François Masson
\nCette conférence ser
 a prononcée (en anglais) par la professeur Julianne Gibbs de l'Universi
 té de l'Alberta.
\nRésuméOur group is interested in understanding how c
 onfinement influences molecular recognition in materials systems and how w
 e can use its unique influence to achieve new material properties. In one 
 example\, we have developed a DNA system that can self-replicate isotherma
 lly by balancing repulsive and attractive interactions during DNA recognit
 ion. This strategy of amplification by destabilization has great potential
  in DNA diagnostics and infectious disease detection as it utilizes very s
 imple DNA modifications and can be performed at virtually any temperature.
  In another example\, we have shown that using molecular recognition we ca
 n control the composition and behavior in DNA nanomaterials that are poten
 tial candidates for targeted drug delivery.  By exploring the unique mole
 cular recognition properties of these same materials\, we have also uncove
 red a strategy for rapid colorimetric detection of DNA suitable for point-
 of-care diagnostics.  Finally\, I will discuss how confinement at planar 
 silica surfaces most relevant to microarray technologies influences DNA re
 cognition using surface specific spectroscopy. We find that confinement at
  the silica interface greatly reduces the stability of DNA duplexes in com
 parison with other common substrates like gold\, which has direct implicat
 ions for biodiagnostics using DNA immobilized on glass.
\nInformations sup
 plémentairesAnnonce PDF de la conférence
END:VEVENT
BEGIN:VTIMEZONE
TZID:America/Montreal
X-LIC-LOCATION:America/Montreal
END:VTIMEZONE
END:VCALENDAR