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DTSTART:20170508T113000
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URL:https://murmitoyen.com/events/vanille/udem/detail/756084-lanthanide-bas
 ed-nanoparticles-as-potential-versatile-bioprobes
LOCATION:Université de Montréal - Pavillon J.-Armand-Bombardier\, 5155\, 
 chemin de la rampe \, Montréal\, QC\, Canada\, H3T 2B2
SUMMARY:Lanthanide-based nanoparticles as potential versatile bioprobes
DESCRIPTION:Eva Hemmer\, Department of Chemistry and Biomolecular Sciences
 Université d'Ottawa
\nAbstract :Lanthanide (Ln3+)-based nanoparticles (Ln
 -NPs) are outstanding candidates for a whole gamut of applications ranging
  from biomedicine to telecommunication\, phosphors\, and more recently ene
 rgy conversion technologies. Those applications are based on the optical p
 roperties of the Ln3+ ions. When doped in appropriate host materials\, nar
 row optical absorption and emission bands as well as long lifetimes of the
  excited electronic states of the Ln3+ are obtained. Following a stepwise 
 excitation with near-infrared (NIR) light\, Ln-NPs show upconversion emiss
 ion spanning the range from UV to visible and NIR. In addition\, NIR light
  of longer wavelengths (> 1000 nm) can be emitted when appropriate Ln3+ do
 pants are chosen.
\nThe use of NIR light is of particular interest for bio
 medical applications since these emission wavelengths perfectly match the 
 biological transparency windows. This sets the basis for deeper penetratio
 n depth into biological tissues due to less absorption\, higher resolution
  as a result of reduced scattering\, and improved imaging contrast due to 
 tissue autofluorescence minimization\; all being inevitable requirements f
 or optical in-vivo bioimaging. Moreover\, the emission profile of Ln-NPs i
 s sensitive to their thermal environment\, thus allowing for application a
 s optical temperature sensors\, while upconverting nanoparticles have also
  been suggested as remote controlled photodynamic agents. Consequently\, e
 fficient upconverters and NIR emitters are highly sought after to push cur
 rent limitations in penetration depth\, spatial resolution\, and upconvers
 ion efficiency. Besides oxides including Gd2O3 or Y2O3\, fluorides\, such 
 as NaGdF4\, are commonly considered as suitable host materials and their p
 reparation via the thermal decomposition process has been widely studied. 
 Seeking better control over reaction conditions allowing for a more precis
 e size\, morphology and crystalline phase control\, their microwave- assis
 ted synthesis provides an attractive alternative.
\nBesides shining a ligh
 t on the potential of Ln-NPs for various applications\, some synthetic str
 ategies towards multifunctional Ln-NPs followed by our lab will be present
 ed.
\nTo find out more about Prof. Hemmer's research\, you can consult her
  web page: 
\nwww.hemmerlab.com
\nCette conférence est présentée par l
 e RQMP Versant Nord du Département de physique de l'Université de Mo
 ntréal et de Génie physique de la Polytechnique.
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