BEGIN:VCALENDAR
VERSION:2.0
PRODID:https://murmitoyen.com/events/vanille/udem/
X-WR-TIMEZONE:America/Montreal
BEGIN:VEVENT
UID:69dbc5170e71d
DTSTAMP:20260412T121519
DTSTART:20170407T110000
SEQUENCE:0
TRANSP:OPAQUE
DTEND:20170407T110000
URL:https://murmitoyen.com/events/vanille/udem/detail/740397-seminaire-de-l
 etudiante-saher-hasan-siddiqui-groupe-charette-
LOCATION:Pavillon Roger-Gaudry \, 2900\, boul. Édouard-Montpetit\, Local M
 -415\, Montréal\, QC\, Canada
SUMMARY:Séminaire de l'étudiante Saher Hasan Siddiqui ( Groupe Charette )
DESCRIPTION:Titre : Catalytic and Asymmetric Cyclopropanation of Functional
 ized Alkenes to Access Useful Building Blocks
\nEndroit : Pavillon Roger-G
 audry\, salle G-415 à 11 h 00.
\nCette conférence sera prononcée par 
 Madame Saher Hasan Siddiqui\, étudiante au doctorat du laboratoire d'And
 ré Charette\, professeur au Département de chimie de l'Université de Mo
 ntréal.
\nRÉSUMÉ:Cyclopropanes have attracted considerable interest by 
 both physical and organic chemists due to their inherent strain and its im
 portance in naturally occurring compounds. Functionalized cyclopropanes ar
 e widely used in pharmaceutically and agrochemically relevant compounds an
 d therefore organic chemists have been challenged to develop efficient and
  robust enantioselective methodology for their synthesis. The presented wo
 rk will focus primarily on the development of a non-oxidative work up for 
 the dioxaborolane-mediated enantioselective cyclopropanation followed by t
 he study of a novel class of chiral rhodium dimer complexes and their effe
 ctiveness towards synthesizing enantiopure cyclopropanes via decomposition
  of diazoalkanes. The enantioselective cyclopropanation of allylic alcohol
 s using the bifunctional chiral controller\, dioxaborolane\, affords the c
 orresponding cyclopropylmethanol derivatives in high yields and enantiosel
 ectivities. Upon completion\, strongly oxidative or a highly basic work up
  to liberate the boron-ligated cyclopropylmethanol derivatives limits acce
 ss to base-sensitive functionalities. Thus\, a modified non-oxidative work
  up allows for improved functional group compatibility and affords base-se
 nsitive cyclopropylmethanol derivatives. An alternative to synthesize enan
 tiopure cyclopropanes has been established with rhodium(II) carboxamidate 
 complexes via the decomposition of diazoalkanes. Therefore the synthesis o
 f novel chiral rhodium diketopiperazine complexes and a study of their sta
 bility\, reactivity and selectivity will be presented for asymmetric cyclo
 propanation reactions.
\nInformation supplémentaireAnnonce PDF du sémina
 ire
END:VEVENT
BEGIN:VTIMEZONE
TZID:America/Montreal
X-LIC-LOCATION:America/Montreal
END:VTIMEZONE
END:VCALENDAR