Titre : Oxygen-Driven Fragment Coupling by Activation of C-H, N-H, and O-H Bonds.
Endroit : Pavillon Roger-Gaudry, salle N-615 à 11 h.
Hôte : Hélène Lebel.
La conférence sera prononcée (en anglais) par la professeure Marisa Kozlowski du Département de chimie de l'University of Pennsylvania. Elle est commanditée par le Centre en chimie verte et catalyse (CCVC).
Résumé : Inspired by Nature's use of oxidative couplings to construct carbon-carbon, carbon-oxygen, and carbon-nitrogen bonds in many natural products, we have undertaken studies of these important transformations. The development of selective catalytic processes for naphthol coupling, phenol coupling, N-arylation, and alkyl C–H acivation that utilize oxygen as the terminal oxidant will be discussed. Applications to the synthesis of chiral natural products including nigerone, hypocrellin, cercosporin, and bisoranjidiol as well as to the synthesis of novel optically active materials will be presented.
