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DTSTAMP:20260415T042300
DTSTART:20140912T140000
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DTEND:20140912T153000
URL:https://murmitoyen.com/events/vanille/udem/detail/453629
LOCATION:Université de Montréal - Pavillon Roger-Gaudry\, 2900\, chemin d
 e la Tour\, Montréal\, QC\, Canada\, H3T 1J6
SUMMARY:Conférence du Professeur Tuan Vo-Dinh (Duke)
DESCRIPTION:Titre : Plasmonic Nanosystems: New Tools for Early Diagnostics 
 and Therapy.Cette conférence sera prononcée (en anglais) par le Profess
 eur Tuan Vo-Dinh\, du Département d'ingénierie biomédicale de la Duke U
 niversity.Résumé : This lecture presents the development and application
  of nanosensor and nanoprobe technology for early biomedical diagnostics a
 nd therapy. This presentation describes several areas of research at the n
 exus of engineering\, biology\, medicine and nanotechnology: (1) plasmonic
 s nanoprobes and nanochips using surface-enhanced Raman scattering (SERS) 
 for multiplex detection\; (2) nanosensors for in vivo analysis of a single
  cell for molecular diagnostics\; and (3) multi-modality nanoplatforms for
  cancer theranostics\, combining detection and therapy. A new generation o
 f nanosensors and nanoprobes combining bio-recognition and nanotechnology 
 has been developed for in vivo monitoring of biochemical processes in a si
 ngle living cell. These studies demonstrate the applications of a new type
  of SERS plasmonics “molecular sentinel” nanoprobes for detection of m
 RNA/microRNA biomarkers for cancer and infectious diseases. The use of nan
 obiosensors allows for measurements of apoptotic signaling pathways inside
  a single cell treated with anticancer drug. Also\, new multi-modality nan
 oprobes provide a unique nanoplatform with capabilities to perform pre-ope
 rative tumor scanning with magnetic resonance imaging (MRI) and X-ray comp
 uted tomography (CT)\, intra-operative tumor detection with surface-enhanc
 ed Raman scattering (SERS) and two-photon luminescence (TPL) as well as po
 st-operative photothermal therapy (PTT). Such nanoprobes open new horizons
  to a host of applications in biomedical diagnostics at the point of care\
 , global health\, molecular imaging\, biology research\, ultra-high throug
 hput screening\, and investigations of the therapeutic action of pharmaceu
 tical agents. Information supplémentaire
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