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UID:6829c1a6414e0
DTSTAMP:20250518T071654
DTSTART:20110210T113000
SEQUENCE:0
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DTEND:20110210T123000
URL:https://murmitoyen.com/events/vanille/udem/detail/32373
LOCATION:Université de Montréal - Pavillon Claire-McNicoll\, 2900\, chemi
 n de la Tour\, Montréal\, QC\, Canada\, H3T 1J6
SUMMARY:Signalling lymphocyte survival through TRAF1
DESCRIPTION:Conférence du Dr Laurent Sabbagh\, chercheur adjoint\, Centre 
 de Recherche - Hôpital Maisonneuve-Rosemont. Cette conférence sera prono
 ncée en anglais. Résumé Tumour necrosis factor receptors (TNFRs) are a 
 family of receptors involved in transmitting survival and death signals in
  lymphocytes and play a critical role in determining the outcome of an imm
 une response and the maintenance of memory T cells. The role of TRAF1\, an
  adaptor protein involved in linking TNFR family members to downstream sig
 nalling pathways\, in the survival of CD8 memory T cells and the dependenc
 e of the 4-1BB receptor\, a member of the TNFR family\, on TRAF1 in mediat
 ing survival of CD8 T cells will be discussed. Using a systems biology app
 roach novel TRAF1 binding partners have been identified to understand TRAF
 1-dependent-signalling pathways downstream of TNFRs in CD8 T cells. Confé
 rence présentée par le Département de microbiologie et immunologie de l
 'Université de Montréal. Photo crédit : site web du Département de mi
 crobiologie et immunologie
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