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DTSTAMP:20260410T215114
DTSTART:20190313T110000
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URL:https://murmitoyen.com/events/vanille/udem/detail/851506-conference-de-
 chimie-avec-le-professeur-david-palmer-university-of-saskatchewan
LOCATION:Université de Montréal - Pavillon Roger-Gaudry\, 2900\, chemin d
 e la Tour\, Montréal\, QC\, Canada\, H3T 1J6
SUMMARY:Conférence de chimie avec le Professeur David Palmer\, University 
 of Saskatchewan
DESCRIPTION:Titre: Lessons from Nature in Catalysis and Inhibitor Design
\
 n  Endroit: Pavillon Roger-Gaudry\, Salle G-815   Hôte: Joelle Pellet
 ier   Résumé: ''Aldolases have long been of interest to chemists as cat
 alysts for carbon-carbon bond formation. Our laboratory has been studying 
 dihydrodipicolinate synthase (DHDPS)\, an aldolase that catalyzes a key st
 ep in the synthesis of bacterial cell wall peptidoglycan. The enzyme has f
 or decades been considered a target for novel antimicrobial agents. Althou
 gh much is known about the enzyme\, many aspects of DHDPS remain poorly un
 derstood. We have been studying the enzyme from Campylobacter jejuni\, usi
 ng kinetic\, structural\, and biophysical techniques to guide the synthesi
 s of effective and selective inhibitors.''
\n 
\nBiographie: Dave Palmer
  earned his BSc and PhD in Chemistry from Queen's University in Kingston\,
  Ontario. His doctoral thesis on reaction mechanisms in the presence of cy
 clodextrins was completed under the co-supervision of Professors Greg That
 cher and Erwin Buncel. His postdoctoral work in enzymology was carried out
  in the laboratory of Professor John Gerlt at the University of Illinois\,
  Urbana-Champaign.Dave joined the Department of Chemistry at the Universit
 y of Saskatchewan in 1999. He has served as Head of that department since 
 2010. Dave was the Program Chair of the Biological and Medicinal Chemistry
  Program for the 88th Canadian Chemistry Conference and Exhibition (CSC200
 5)\, and is a co-founder of the Western Canadian Medicinal Chemistry Works
 hop. He has served on the NSERC Discovery Grant Evaluation Group for Chemi
 stry since 2018\, and will serve as Co-chair for the 2020 competition.
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