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DTSTART:20170330T110000
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URL:https://murmitoyen.com/events/vanille/udem/detail/737878-conference-rog
 er-barre-avec-la-professeur-frances-arnold-caltech
LOCATION:Pavillon Roger-Gaudry \, 2900\, boul. Édouard-Montpetit\, Local M
 -415\, Montréal\, QC\, Canada
SUMMARY:Conférence Roger-Barré avec la Professeur Frances Arnold ( CALTEC
 H)
DESCRIPTION:Titre 1 : ''Innovation by evolution: expanding the enzyme unive
 rse'' (30 mars 2017)
\nTitre 2: “Bringing new chemistry to life” (31 m
 ars 2017)
\nEndroit : Pavillon Roger-Gaudry\, salle M-415 à 11 h.Hôte :
  Professeur Shawn Collins
\nCette conférence sera prononcée (en anglai
 s) par la Professeure Frances Arnold de la California Institute of Techn
 ology (Caltech).
\nRésumé :Not satisfied with nature’s vast catalytic 
 repertoire\, we want to create new enzymes and expand the space of genetic
 ally encoded chemical reactions. I will describe how we can use the most p
 owerful biological design process\, evolution\, to optimize existing enzym
 es and invent new ones. Mimicking nature’s evolutionary tricks and using
  a little chemical intuition\, we can generate whole new enzyme families t
 hat catalyze important reactions not (yet) known in nature\, thereby addin
 g new capabilities to the chemistry of the biological world and increasing
  the scope of molecules and materials we can build. I will show that heme 
 proteins can catalyze an array of increasingly challenging carbene- and ni
 trene-transfer reactions and that these new activities can be enhanced by 
 directed evolution. Unlike small-molecule catalysts described for some of 
 these reactions\, the new heme enzymes are made microbially from renewable
  resources\, use earth-abundant iron\, function in aqueous media under amb
 ient conditions\, and are highly selective.
\nBiographie : As Dickinson Pr
 ofessor at the California Institute of Technology\, Frances Arnold’s res
 earch focuses on protein engineering by directed evolution\, with applicat
 ions in alternative energy\, chemicals\, and medicine. She has a BS in Mec
 hanical and Aerospace Engineering from Princeton University and a PhD in c
 hemical engineering from UC Berkeley. Dr. Arnold’s honors include the Mi
 llennium Technology Prize (2016)\, the Eni Prize in Renewable and Nonconve
 ntional Energy (2013)\, the US National Medal of Technology and Innovation
  (2011)\, and the Charles Stark Draper Prize of the US National Academy of
  Engineering (2011). She was inducted into the US National Inventors Hall 
 of Fame in 2014 and has been elected to membership in all three US Nationa
 l Academies\, of Science\, Medicine\, and Engineering. She was elected to 
 the American Academy of Arts and Sciences in 2011 and has honorary doctora
 tes from Stockholm University\, the ETH Zurich\, and the University of Chi
 cago. Arnold chairs the Advisory Panel of the David and Lucile Packard Fou
 ndation Fellowships in Science and Engineering program and serves as a jud
 ge for the Queen Elizabeth Prize in Engineering.
\nArnold holds more than 
 50 US patents and is active in technology transfer. She is a Director of I
 llumina and Provivi and has served on numerous science advisory boards. Sh
 e co-founded Gevo\, Inc. in 2005 to make fuels and chemicals from renewabl
 e resources and Provivi\, Inc. in 2013 to develop non-toxic modes of agric
 ultural pest control.
\nInformation supplémentaireBrochure de la confér
 ence
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