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DTSTAMP:20260413T233227
DTSTART:20151005T143000
SEQUENCE:0
TRANSP:OPAQUE
DTEND:20151005T160000
URL:https://murmitoyen.com/events/vanille/udem/detail/627097
LOCATION:Université de Montréal - Pavillon Roger-Gaudry\, 2900\, chemin d
 e la Tour\, Montréal\, QC\, Canada\, H3T 1J6
SUMMARY:Conférence CCVC avec le Professeur Nicholas Turner (Manchester)
DESCRIPTION:Titre : Cascade Reactions via Amine Biocatalysis.Endroit : Pavi
 llon Roger-Gaudry\, salle G-1015\, exceptionnellement un lundi à 14 h 30.
 Hôte : Joelle Pelletier.
\nLa conférence sera prononcée en anglais par 
 le professeur Nicholas Turner de l'École de chimie de l'University of Man
 chester. Elle est commanditée par le Centre en chimie verte et catalyse 
 (CCVC).
\nRésumé : This lecture will describe recent work from our labor
 atory aimed at developing new biocatalysts for enantioselective organic sy
 nthesis\, with a particular emphasis on enzymes involved in amine biocatal
 ysis. By applying the principles of ‘biocatalytic retrosynthesis’ it i
 s possible to design new synthetic routes to target molecules in which bio
 catalysts are used in the key bond forming steps. The integration of sever
 al biocatalytic transformations into multi-enzyme cascade systems has also
  been a focus of recent work in our laboratories. In this context MAO-N ha
 s been used in combination with other biocatalysts and chemocatalysts in o
 rder to complete a cascade of enzymatic reactions. Other engineered biocat
 alysts that can be used in the context of cascade reactions include ω-tra
 nsaminases\, phenylalanine ammonia lyases\, amine dehydrogenases\, imine r
 eductases and artificial enzymes. We are also developing combined oxidase/
 metal-catalyst systems for the selective oxidation of amines and alcohols 
 to amides/lactams/aldehydes and carboxylic acids.
\nInformation supplémen
 taireAnnonce PDF de la conférence
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