BEGIN:VCALENDAR
VERSION:2.0
PRODID:https://murmitoyen.com/events/vanille/udem/
X-WR-TIMEZONE:America/Montreal
BEGIN:VEVENT
UID:69e20416b6bcf
DTSTAMP:20260417T055742
DTSTART:20120713T110000
SEQUENCE:0
TRANSP:OPAQUE
DTEND:20120713T123000
URL:https://murmitoyen.com/events/vanille/udem/detail/134667
LOCATION:Université de Montréal - Pavillon J.-Armand-Bombardier\, 5155\, 
 chemin de la rampe \, Montréal\, QC\, Canada\, H3T 2B2
SUMMARY:Conférence du Professeur Alex Bunker (Helsinki)
DESCRIPTION:Titre : Poly(ethylene glycol) in drug delivery\, why does it w
 ork\, and can we do better? All atom molecular dynamics simulation provid
 es some answers. .La conférence sera prononcée par le professeur Alex 
 Bunker du Centre for Drug Research de l'Université d'Helsinki (Finlande).
  Elle sera donnée en anglais.Résumé : Poly(ethylene glycol) (PEG) has a
 n important role in drug delivery as a protective coating in pharmaceutica
 l nanotechnology\,  or as a covalently bound congugate of drug molecules.
  The mechanism through which PEG performs its function is not clearly unde
 rstood. This is a highly relevant issue\, as the search for a a superior a
 lternative polymer to PEG is a very active field. We have used all atom mo
 lecular dynamics simulation to study this. We have performed simulations o
 f the PEGylated liposome surface. We have studies the effect of liposome f
 ormulation\, and interactions with salt ions in the bloodstream and target
 ing ligands on the liposome surface. We have also studied the interaction 
 between PEG and three drugs for which it is used as a delivery aid: paclit
 axel\, piroxicam\, and hematoporphyrin. Information supplémentaire
END:VEVENT
BEGIN:VTIMEZONE
TZID:America/Montreal
X-LIC-LOCATION:America/Montreal
END:VTIMEZONE
END:VCALENDAR